Biosensor AssaysBiosensor Assays

Measuring Biochemical Pathways in High Throughput Screening

Previously, it could take months or years to develop assays for a new target. Our platform makes that possible in a matter of weeks. We screen small molecules and biologics in living human cells using engineered fluorescent biosensor proteins.

Our ever-growing biosensor gene library enables us to rapidly build high-throughput screening tools for a wide range of drug targets.

Our Biosensors Measure Target Activity Effects at Specific Subcellular Locations

Biosensor Assays
Our Growing Assay Toolbox

cAMP
ERK
EGFR
IR
IGFR
PKC
GLP1R
KIF1A
TACE
Ca2+
AKT

Why Live Cells?

Capture Drug Effects that Require Complex Molecular Interactions Within the Native Cellular Ecosystem

Live-cell biosensor assays enable continuous monitoring of challenging targets at specific locations in intact signaling networks. Traditional cell-free and destructive assays are frequently unsuitable for detecting sub-cellular protein activities, and overlook the complexity of target function in a signaling network. Live-cells balance physiological relevance with scalability.

Let’s create and find rare variants that work.

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