Mega Throughput Screening of Reporter Cell Lines
We create millions of biosensor variants, test each individually using live-cell imaging, and isolate rare variant cells that contain robust biosensors for a targeted molecular activity.
Our biosensors change shape in living cells in response to engagement with specific drug targets, effectively converting target activity into a measurable signal as modulations of FRET (Förster Resonance Energy Transfer).
Our process requires no prior knowledge other than a single chemical activator or repressor of your molecular target.
We strive to create the most quantitative bioassays on the market.